Figure 5From: The 2D Hotelling filter - a quantitative noise-reducing principal-component filter for dynamic PET data, with applications in patient dose reduction Time-activity uptake curves. Comparing time-activity curves in blood and metastasis region-of-interests in the same data as Figure 4. Original data (diamonds for metastases, squares for blood) and Hotelling filtered data (lines). This ROI-based time-activity graph shows preserved quantitation and the removal of noise can be seen for the metastasis curve.Back to article page