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Table 2 Laboratory values (mean ± SD) of the 20 patients at each time point and corresponding one-way Anova P values across all time points.

From: Toxicology evaluation of radiotracer doses of 3'-deoxy-3'-[18F]fluorothymidine (18F-FLT) for human PET imaging: Laboratory analysis of serial blood samples and comparison to previously investigated therapeutic FLT doses

 

Pre-FLT

Immediate <5 h

5 – 24 Hours

1 – 7 days

> 1 week

P

Sodium (mEq/L ± SD)

139.4 ± 1.5

138.2 ± 2.1

138.3 ± 2.0

137.5 ± 1.8

138.1 ± 2.3

0.064

Potassium (mEq/L ± SD)

4.2 ± 0.5

4.2 ± 0.4

4.1 ± 0.4

4.2 ± 0.3

4.2 ± 0.4

0.968

Chloride (mEq/L ± SD)

102.3 ± 3.3

104.2 ± 3.7

104 ± 3.8

102.3 ± 2.4

101.2 ± 3.1

0.055

Glucose (mg/dL ± SD)

95.1 ± 14.8

96.6 ± 20.7

98.5 ± 23.1

105.4 ± 17.7

109.5 ± 14.6

0.175

Creatinine (mg/dL ± SD)

0.885 ± 0.198

0.882 ± 0.207

0.881 ± 0.180

0.910 ± 0.190

0.844 ± 0.217

0.949

BUN (mg/dL ± SD)

15.8 ± 5.0

15.1 ± 5.6

15.2 ± 6.3

14.3 ± 5.2

15.3 ± 5.7

0.959

SGOT (U/L ± SD)

20.8 ± 5.0

22.0 ± 5.1

22.0 ± 5.3

22.2 ± 11.4

21.8 ± 6.7

0.973

SGPT (U/L ± SD)

18.7 ± 6.7

18.5 ± 6.6

19.1 ± 6.5

17.6 ± 5.3

17.2 ± 6.5

0.978

Albumin (g/dL ± SD)

3.9 ± 0.5

3.5 ± 0.4

3.44 ± 0.3

3.1 ± 0.6

3.2 ± 0.8

0.003

Alk Phos (U/L ± SD)

73.8 ± 19.4

61.1 ± 14.7

58.3 ± 17.0

59.5 ± 22.7

 

0.081

Bilirubin (mg/dL ± SD)

0.647 ± 0.181

0.573 ± 0.246

0.581 ± 0.263

0.621 ± 0.286

0.752 ± 0.418

0.714

RBC (x10 6 /μL ± SD)

4.5 ± 0.4

4.3 ± 0.5

4.2 ± 0.5

3.8 ± 0.3

3.7 ± 0.4

<0.0001

Hematocrit (% ± SD)

40.9 ± 3.1

39.1 ± 4.4

38.4 ± 4.0

35.2 ± 3.4

35.0 ± 3.4

<0.0001

WBC (x10 3 /μL ± SD)

7.6 ± 2.1

7.7 ± 3.4

7.9 ± 3.3

9.5 ± 2.8

9.0 ± 3.2

0.262

Platelets (x10 3 /μL ± SD)

278.1 ± 96.8

259.1 ± 103.1

255.9 ± 103.0

230.1 ± 76.7

233.5 ± 69.5

0.674