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Table 4 RECIST, WHO and volume analyses from US and MR images of Gammex/UTHSCSA Mark 2 phantom

From: Preclinical multimodality phantom design for quality assurance of tumor size measurement

 

Design

Image RECIST and WHO (mean ± SD (% error))

  

US

MRI

RECIST (mm)

37.00

39.09 ± 0.52 (+5.66 ± 1.41%)

37.15 ± 0.94 (+0.39 ± 2.54%)

WHO (mm 2 )

365.00

355.44 ± 4.69 (-0.16 ± 1.32%)

348.69 ± 9.95 (-2.05 ± 2.79%)

 

Design

Image Volume (mean ± SD (% error))

  

US

MRI

Volume (mm 3 )

4.19 (2 mm sphere)

4.37 ± 0.40 (+4.40 ± 9.47%)

3.28 ± 2.79 (-21.81 ± 66.60%)

 

33.51 (4 mm sphere)

35.93 ± 1.89 (+7.29 ± 5.65%)

37.46 ± 7.24 (+11.86 ± 21.62%)

 

179.59 (7 mm sphere)

169.38 ± 2.85 (-5.69 ± 1.59%)

155.43 ± 29.57 (-13.45 ± 16.46%)

 

523.60 (10 mm sphere)

544.50 ± 10.65 (+3.99 ± 2.03%)

484.32 ± 25.94 (-7.50 ± 4.95%)

 

1436.76 (14 mm sphere)

1453.39 ± 9.42 (+1.21 ± 0.66%)

1381.45 ± 32.07 (-3.80 ± 2.23%)

 

Slope [95% CI]

1.014 ± 0.009 [0.984 to 1.043]

0.962 ± 0.011 [0.928 to 0.996]

 

Intercept [95% CI]

-0.152 ± 6.341 [-20.33 to 20.02]

-6.665 ± 7.357 [-30.08 to 16.75]

 

R 2

0.9998

0.9996

 

p-value

< 0.0001

< 0.0001

  1. Mean ± standard deviation (SD) for three repeated measures and % errors in parenthesis are shown for RECIST, WHO and volume analysis. The same analysis methods as described for the Mark 1 phantom were used. Slope and intercepts [95% confidence intervals], correlation coefficient (R2) and p-value of linear regression lines for volume of test objects also are shown.