Table 5 RECIST, WHO and volume analyses from US, CT and MR images of UTHSCSA multimodality tumor measurement phantom
From: Preclinical multimodality phantom design for quality assurance of tumor size measurement
Design | Image RECIST and WHO (mean ± SD (% error)) | |||
|---|---|---|---|---|
US | CT | MRI | ||
RECIST (mm) | 37.00 | 37.05 ± 0.05 (+0.13 ± 0.13%) | 37.62 ± 0.12 (+1.69 ± 0.33%) | 37.39 ± 0.13 (+1.05 ± 0.34%) |
WHO (mm 2 ) | 365.00 | 359.634 ± 0.93 (-1.47 ± 0.25%) | 368.76 ± 1.47 (+1.03 ± 0.39%) | 359.96 ± 2.09 (-1.38 ± 0.57%) |
Image Volume (mean ± SD (% error)) | ||||
US | CT | MRI | ||
Volume (mm 3 ) | 4.19 (2 mm sphere) | 3.55 ± 0.00 (-15.34 ± 0.04%) | 3.42 ± 0.45 (-18.30 ± 10.65%) | 4.43 ± 0.03 (+5.72 ± 0.60%) |
33.51 (4 mm sphere) | 32.76 ± 0.33 (-2.24 ± 0.99%) | 32.56 ± 0.83 (-2.84 ± 2.49%) | 34.05 ± 1.24 (+1.62 ± 3.70%) | |
179.59 (7 mm sphere) | 180.71 ± 1.71 (+0.62 ± 0.95%) | 179.41 ± 4.06 (-0.10 ± 2.26%) | 180.84 ± 4.25 (+0.70 ± 2.36%) | |
523.60 (10 mm sphere) | 520.27 ± 3.19 (-0.64 ± 0.61%) | 537.90 ± 4.08 (+2.73 ± 0.78%) | 495.65 ± 3.97 (-5.34 ± 0.76%) | |
1436.76 (14 mm sphere) | 1408.59 ± 5.67 (-1.96 ± 0.39%) | 1450.39 ± 11.22 (+0.95 ± 0.78%) | 1406.47 ± 8.16 (-2.11 ± 0.57%) | |
Slope [95% CI] | 0.980 ± 0.003 [0.969 to 0.991] | 1.011 ± 0.004 [0.997 to 1.025] | 0.977 ± 0.008 [0.951 to 1.002] | |
Intercept [95% CI] | 2.277 ± 2.261 [-4.919 to 9.472] | 0.413 ± 3.052 [-9.299 to 10.12] | -1.013 ± 5.613 [-18.87 to 16.85] | |
R 2 | 1.000 | 0.9999 | 0.9998 | |
p-value | <0.0001 | <0.0001 | <0.0001 | |