Figure 2From: The 2D Hotelling filter - a quantitative noise-reducing principal-component filter for dynamic PET data, with applications in patient dose reduction Residuals in 2D and 3D Hotelling filter. The residual for Raclopride plotted as a function of time for striatum and cerebellum ROIs. The residual represents the difference between filtered and original data, and is thus a measure of the bias at each time frame. A) 3D Hotelling filter (PC1-4), which displays a large time-varying error. B) 2D Hotelling filter (PC1-4), where the striatal uptake displays a considerably lower error.Back to article page